Stem cells

Period of duration of course
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Course info
Number of course hours
20
Number of hours of lecturers of reference
20
Number of hours of supplementary teaching
0
CFU 3
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Type of exam

Oral exam

Lecturer

View lecturer details

Prerequisites

Knowledge of cellular, molecular and developmental biology; anatomy of the central nervous system. PhD course in Neuroscience (I-IV year).

Programme

Stem cells: their potential and their niche. Division and self-renewal. Plutipotent stem cells. Adult stem cell niches. Hematopoietic stem cells. Cell reprogramming and the human cell model to study development and disease. Neural stem cells as progenitor cells. Isolation and culturing of neural stem cells. Neural stem cell heterogeneity. Neural stem cells and neurogenesis. Neurogenesis in adult hippocampus. Cellular organization of the subventricular zone in the ddult human brain: a niche of neural stem cells. The spinal cord neural stem cell niche. Neural stem cells and regenerative medicine.

Educational aims

At the completion of the course students will be able to:

  • Define stem cells
  • Identify types of stem cells
  • Define the detailed steps of neural stem cell formation, maintenance, differentiation and aging
  • Critically analyse scientific papers on neural stem cells
  • Describe the medical uses for neural stem cells

Bibliographical references

Scott F. Gilbert & Michael J. F. Barresi, Developmental Biology, 11th edition, Sinauer Associates, Inc. , Publishers Sunderland, Massac.

Papers in specialized journals.