Development and aging of the nervous system

Academic year 2023/2024
Lecturer Alessandro Cellerino

Examination procedure

Oral exam

Prerequisites

The course requires basic knowledge of Neurophysiology, Developmental Biology, Cellular and Molecular Biology and is dedicated to students of the Master course.Gilbert, Developmental Biology, 2016, Sinauer Associates Kempermann, Adult Neurogenesis II, 2010, Oxford Medicine

Syllabus

1. Evolution of aging and its relationship with development
2. Adult neurogenesis I
3. Adult neurogenesis II
4. Brain aging: morphologicical changes
5. Brain aging: fucntional changes and the role of systemic factors
6. Brain aging: expression profiling studies
7. Circadian rhythms, sleep and aging
8. IGF-I and calorie restriction
9. Pharmacological interventions into aging
10. Human aging: physiology and genetic inffluence

Bibliographical references

Gilbert, Developmental Biology, 2016, Sinauer Associates
Kempermann, Adult Neurogenesis II, 2010, Oxford
Medicine